Download Files:
Products Details
Product Description
– LY125180 is a competitive inhibitor of the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06, 2.2 and 2.5 μM respectively[1].
Web ID
– HY-129682
Shipping
– Room temperature
Molecular Formula
– C18H24ClNO
References
– [1]Wong DT, et al. N,N-Dimethyl-alpha-[2-(p-tolyloxy)ethyl]benzylamine hydrochloride (LY125180). Effects on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo. Biochem Pharmacol. 1980 Mar 15;29(6):935-41.
CAS Number
– 74515-39-2
Molecular Weight
– 305.84
SMILES
– CC1=CC=C(OCCC(C2=CC=CC=C2)N(C)C)C=C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Adrenergic Receptor;Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
