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Products Details
Product Description
– LY125180 is a competitive inhibitor of the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06, 2.2 and 2.5 μM respectively[1].
Web ID
– HY-129682
Shipping
– Room temperature
Molecular Formula
– C18H24ClNO
References
– [1]Wong DT, et al. N,N-Dimethyl-alpha-[2-(p-tolyloxy)ethyl]benzylamine hydrochloride (LY125180). Effects on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo. Biochem Pharmacol. 1980 Mar 15;29(6):935-41.
CAS Number
– 74515-39-2
Molecular Weight
– 305.84
SMILES
– CC1=CC=C(OCCC(C2=CC=CC=C2)N(C)C)C=C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Adrenergic Receptor;Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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