LUF7244

$215

Only 1000 item(s) left in stock.

Products Details

Product Description

– LUF7244 is a selective allosteric modulator of Kv11.1 channels. LUF7244 inhibits early afterdepolarizations. LUF7244 can be used for anti-arrhythmia research[1].

Web ID

– HY-137986

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H15ClN2O3

References

– [1]Qile M, et, al. LUF7244, an allosteric modulator/activator of Kv 11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model. Br J Pharmacol. 2019 Oct;176(19):3871-3885.

CAS Number

– 1821638-43-0

Molecular Weight

– 366.80

SMILES

– O=C(NC1=CC=CN=C1)COC2=CC=C(C(C3=CC=CC(Cl)=C3)=O)C=C2

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Potassium Channel

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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