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Lucanthone
$65 – $1,300
Products Details
Product Description
– Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).
Web ID
– HY-B2098
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H24N2OS
References
– [1]Chowdhury SM, et al. Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme. Nanomedicine. 2015 Jan;11(1):109-18.|[2]Carew JS, et al. Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. J Biol Chem. 2011 Feb 25;286(8):6602-13.
CAS Number
– 479-50-5
Molecular Weight
– 340.48
Compound Purity
– 99.75
SMILES
– O=C1C2=C(SC3=C1C=CC=C3)C(C)=CC=C2NCCN(CC)CC
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– Autophagy;Parasite
Pathway
– Anti-infection;Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
