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Products Details
Product Description
– Lu AA47070 is a phosphonooxymethylene prodrug of a potent and selective Adenosine A2A receptor antagonist. Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade[1][2].
Web ID
– HY-14408
Shipping
– Room temperature
Molecular Formula
– C17H20F2N3O6PS
References
– [1]Discovery of Phosphoric Acid Mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} Ester (Lu AA47070): A Phosphonooxymethylene Prodrug of a Potent and Selective hA2A Receptor Antagonist
J. Med. Chem., Article ASAP
DOI: 10.1021/jm1008659
Publication Date (Web): January 6, 2011|[2]Collins LE, et al. The novel adenosine A2A antagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade. Pharmacol Biochem Behav. 2012 Jan;100(3):498-505.
CAS Number
– 913842-25-8
Molecular Weight
– 463.39
SMILES
– O=P(O)(O)OCN1C=CS/C1=NC(C2=CC(F)=C(NC(CC(C)(C)C)=O)C(F)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
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