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LTURM34
SKU
HY-101667-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR, DNA-PK
$80 – $920
Products Details
Product Description
– LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM). LTURM34 exhibits 170-fold selectivity for DNA-PK over PI3K. LTURM34 shows potent antiproliferative activity in a wide range of tumor cell lines[1].
Web ID
– HY-101667
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H18N2O3S
References
– [1]Morrison R, et al. Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur J Med Chem. 2016 Mar 3;110:326-39.
CAS Number
– 1879887-96-3
Molecular Weight
– 414.48
Compound Purity
– 99.89
SMILES
– O=C1C2=CC=CC(C3=CC=CC4=C3SC5=C4C=CC=C5)=C2OC(N6CCOCC6)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 65 mg/mL (ultrasonic)
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.