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LSP-249
SKU
HY-126378-1 mg
Category Reference compound
Tags Inflammation/Immunology, Metabolic Enzyme/Protease, Ser/Thr Protease
$38 – $650
Products Details
Product Description
– LSP-249 (example 35), extracted from patent WO2016011209A1, is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell[1].
Web ID
– HY-126378
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H22ClN5O
References
– [1]Andrew Mcdonald, et al. Therapeutic inhibitory compounds. Patent. WO2016011209A1.
CAS Number
– 1801253-04-2
Molecular Weight
– 431.92
Compound Purity
– 99.98
SMILES
– O=C(C1=CC(CC2=CC=C3N=CC(Cl)=CC3=C2)=NC=C1)NCC4=C(C)C=C(N)N=C4C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.