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Product Description
– LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].
Web ID
– HY-149213
Shipping
– Room temperature
Molecular Formula
– C18H20N2OS
References
– [1]Xing-Jie Dai, et al. Phenothiazine-Based LSD1 Inhibitor Promotes T-Cell Killing Response of Gastric Cancer Cells. J Med Chem. 2023 Mar 23;66(6):3896-3916.
CAS Number
– 4734-59-2
Molecular Weight
– 312.43
SMILES
– N1(CCN2C3=C(SC4=C2C=CC=C4)C=CC=C3)CCOCC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase;PD-1/PD-L1
Pathway
– Epigenetics;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
