Products Details

Product Description

– LSD1-IN-23 is a competitive/non-competitive mixed inhibitor of lysine specific demethylase 1 (LSD1). LSD1-IN-23 has LSD1 inhibitory activity with an IC50 value of 0.58 μM. LSD1-IN-23 can be used for the research of neuroblastoma (NB)[1].

Web ID

– HY-152032

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C19H13BrClN5O2S

References

– [1]Catherine M Mills, et al. Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma. Eur J Med Chem. 2022 Dec 15;244:114818.

Molecular Weight

– 490.76

SMILES

– O=S(NC(C=CC(Br)=C1)=C1C2=NNN=N2)(C3=CC=C(C=C3)C4=CC=C(C=C4)Cl)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Histone Demethylase

Isoform

– KDM1/LSD1

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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