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Products Details
Product Description
– LSD1-IN-23 is a competitive/non-competitive mixed inhibitor of lysine specific demethylase 1 (LSD1). LSD1-IN-23 has LSD1 inhibitory activity with an IC50 value of 0.58 μM. LSD1-IN-23 can be used for the research of neuroblastoma (NB)[1].
Web ID
– HY-152032
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H13BrClN5O2S
References
– [1]Catherine M Mills, et al. Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma. Eur J Med Chem. 2022 Dec 15;244:114818.
Molecular Weight
– 490.76
SMILES
– O=S(NC(C=CC(Br)=C1)=C1C2=NNN=N2)(C3=CC=C(C=C3)C4=CC=C(C=C4)Cl)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase
Isoform
– KDM1/LSD1
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
