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Products Details
Product Description
– LSD1-IN-17 (compound 5b) is a potent LSD1 inhibitor. LSD1-IN-17 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.005, 0.028, and 0.820 μM, respectively. LSD1-IN-17 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 17.2 μM[1].
Web ID
– HY-144758
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H18N2OS
References
– [1]Fioravanti R, et al. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. J Enzyme Inhib Med Chem. 2022 Dec;37(1):973-985.
Molecular Weight
– 334.43
SMILES
– NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CSC=C4)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase;Monoamine Oxidase
Isoform
– KDM1/LSD1;MAO-A;MAO-B
Pathway
– Epigenetics;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
