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Products Details
Product Description
– LSD1-IN-14 is a potent and selective LSD1 inhibitor (IC50=0.89 μM). LSD1-IN-14 can significantly inhibit the proliferation of A549 and THP-1 cells and induce the apoptosis of tumor cells[1].
Web ID
– HY-145861
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H24FN5
References
– [1]Wang X, et al. Design, synthesis and biological evaluation of 2-aminopyrimidine-based LSD1 inhibitors. Bioorg Chem. 2022;121:105699.
CAS Number
– 2698340-11-1
Molecular Weight
– 365.45
SMILES
– CN(CCN(C1=CC=C(C=C1)NC2=NC=C(C=N2)C3=CC=C(C=C3)F)C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Histone Demethylase
Isoform
– KDM1/LSD1
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
