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Products Details
Product Description
– Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research[1].
Web ID
– HY-142774
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C25H21F5N4O3
References
– [1]Qiong Xiao, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. CN112574221B.
CAS Number
– 2637485-13-1
Molecular Weight
– 520.45
SMILES
– O=C1N=C(C=C2N1CC34N2C(CC4)CCC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC(C(F)(F)F)=NC=C6
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Phospholipase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
