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Products Details
Product Description
– Lp-PLA2-IN-2 is a potent and selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2[1].
Web ID
– HY-133148
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H23FN2O4S
References
– [1]Woolford AJ, et al. Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2). J Med Chem. 2016 Dec 8;59(23):10738-10749.
CAS Number
– 2071636-15-0
Molecular Weight
– 394.46
SMILES
– N#CC1=CC(OCCN2C(C[C@@H](C(CC3)(C)CCS3(=O)=O)C2)=O)=CC=C1F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Phospholipase
Isoform
– Phospholipase A
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
