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Loratadine n-oxide
SKU
HY-147085-Get quote
Category Reference compound
Tags GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling, Histamine Receptor, Inflammation/Immunology
Products Details
Product Description
– Loratadine n-oxide is a metabolite of Loratadine. Loratadine n-oxide shows antihistamine activity[1].
Web ID
– HY-147085
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H23ClN2O3
References
– [1]Stone EA, et al. Asymmetric Catalysis upon Helically Chiral Loratadine Analogues Unveils Enantiomer-Dependent Antihistamine Activity. J Am Chem Soc. 2020 Jul 22;142(29):12690-12698.
CAS Number
– 165739-62-8
Molecular Weight
– 398.88
SMILES
– O=C(N1CC/C(CC1)=C2C3=C(CCC4=CC=C[N+]([O-])=C42)C=C(Cl)C=C3)OCC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.