Products Details

Product Description

– Loratadine n-oxide is a metabolite of Loratadine. Loratadine n-oxide shows antihistamine activity[1].

Web ID

– HY-147085

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H23ClN2O3

References

– [1]Stone EA, et al. Asymmetric Catalysis upon Helically Chiral Loratadine Analogues Unveils Enantiomer-Dependent Antihistamine Activity. J Am Chem Soc. 2020 Jul 22;142(29):12690-12698.

CAS Number

– 165739-62-8

Molecular Weight

– 398.88

SMILES

– O=C(N1CC/C(CC1)=C2C3=C(CCC4=CC=C[N+]([O-])=C42)C=C(Cl)C=C3)OCC

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Histamine Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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