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Lomitapide (mesylate)
$75 – $120
Products Details
Product Description
– Lomitapide (AEGR-733; BMS-201038) mesylate is a highly effective MTP protein inhibitor with an in vitro IC50 value of 8nM.
Web ID
– HY-14668
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C40H41F6N3O5S
References
– [1]Sulsky R, et al. 5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5067-70.|[2]Lomitapide. Am J Cardiovasc Drugs. 2011 Oct 1;11(5):347-52.|[3]Perry CM. Lomitapide: a review of its use in adults with homozygous familial hypercholesterolemia. Am J Cardiovasc Drugs. 2013 Aug;13(4):285-96.
CAS Number
– 202914-84-9
Molecular Weight
– 789.83
Compound Purity
– 99.61
SMILES
– O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F.O=S(C)(O)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Microsomal Triglyceride Transfer Protein (MTP)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
