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Lofexidine (hydrochloride)
$35 – $55
Products Details
Product Description
– Lofexidine (hydrochloride) is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2].
Web ID
– HY-B1052
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C11H13Cl3N2O
References
– [1]Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9(11):1371-7.|[2]Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44(2):343-51.
CAS Number
– 21498-08-8
Molecular Weight
– 295.59
Compound Purity
– 99.94
SMILES
– CC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl.[H]Cl
Clinical Information
– Launched
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
