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Products Details
Product Description
– LOE 908 hydrochloride is a non-selective cation channel (NSCC) inhibitor[1].
Web ID
– HY-107756
Shipping
– Room temperature
Molecular Formula
– C41H49ClN2O9
References
– [1]Krautwurst D, et al. The isoquinoline derivative LOE 908 selectively blocks vasopressin-activated nonselective cation currents in A7r5 aortic smooth muscle cells. Naunyn Schmiedebergs Arch Pharmacol. 1994 Mar;349(3):301-7.|[2]Cheney JA, et al. The novel compound LOE 908 attenuates acute neuromotor dysfunction but not cognitive impairment or cortical tissue loss following traumatic brain injury in rats. J Neurotrauma. 2000 Jan;17(1):83-91.
CAS Number
– 143482-60-4
Molecular Weight
– 749.29
SMILES
– COC(C(OC)=C(OC)C=C1)=C1CCN(CCC2=C(C(OC)=C(OC)C=C2)OC)C(C(C3=CC=CC=C3)C4=NCCC5=CC(OC)=C(OC)C=C45)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
