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Lodelaben

$980$2,400

Products Details

Product Description

– Lodelaben is a human neutrophil elastase inhibitor with an IC50 and Ki of 0.5 and 1.5 μM, respectively.

Web ID

– HY-100240

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C25H41ClO3

References

– [1]Nakao A, et al. SC-39026, a specific human neutrophil elastase inhibitor. Biochem Biophys Res Commun. 1987 Sep 15;147(2):666-74.|[2]Ilkiw R, et al. SC-39026, a serine elastase inhibitor, prevents muscularization of peripheral arteries, suggesting a mechanism of monocrotaline-induced pulmonary hypertension in rats. Circ Res. 1989 Apr;64(4):814-25.

CAS Number

– 111149-90-7

Molecular Weight

– 425.04

Compound Purity

– 95.0

SMILES

– O=C(O)C1=CC=C(C(O)CCCCCCCCCCCCCCCCC)C=C1Cl

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Elastase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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