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Lodelaben
SKU
HY-100240-1 mg
Category Reference compound
Tags Elastase, Metabolic Disease; Cardiovascular Disease, Metabolic Enzyme/Protease
$980 – $2,400
Products Details
Product Description
– Lodelaben is a human neutrophil elastase inhibitor with an IC50 and Ki of 0.5 and 1.5 μM, respectively.
Web ID
– HY-100240
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C25H41ClO3
References
– [1]Nakao A, et al. SC-39026, a specific human neutrophil elastase inhibitor. Biochem Biophys Res Commun. 1987 Sep 15;147(2):666-74.|[2]Ilkiw R, et al. SC-39026, a serine elastase inhibitor, prevents muscularization of peripheral arteries, suggesting a mechanism of monocrotaline-induced pulmonary hypertension in rats. Circ Res. 1989 Apr;64(4):814-25.
CAS Number
– 111149-90-7
Molecular Weight
– 425.04
Compound Purity
– 95.0
SMILES
– O=C(O)C1=CC=C(C(O)CCCCCCCCCCCCCCCCC)C=C1Cl
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Elastase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.