LNP Lipid-8

SKU HY-154974-10 mg Category Tags ,

$320$2,780

Products Details

Product Description

– LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model[1].

Web ID

– HY-154974

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C42H71NO7

References

– [1]Lokugamage MP, et al. Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands. Adv Mater. 2019 Oct;31(41):e1902251.

CAS Number

– 2408140-60-1

Molecular Weight

– 702.02

Compound Purity

– 95.0

SMILES

– CCN(CC)CCCOC(OCC(COC(CCCCCCC/C=CC/C=CCCCCC)=O)COC(C[C@@]12CC3C[C@H](C[C@@H](C3)C2)C1)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Others

Pathway

– Others

Product type

– Oligonucleotides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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