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Products Details
Product Description
– LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells[1].
Web ID
– HY-155309
Shipping
– Room temperature
Molecular Formula
– C19H14FNO2
References
– [1]Ahmed Fnaiche, et al. Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg Med Chem Lett. 2023 Oct 15:95:129488.
Molecular Weight
– 307.32
SMILES
– OC(C1=CC=C(F)C=C1NC2=CC(C3=CC=CC=C3)=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– YAP
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
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