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LIMK-IN-1
$101
Only 1000 item(s) left in stock.
Products Details
Product Description
– LIMK-IN-1 (Compound 14) is a LIMK1/2 inhibitor (IC50: 0.5 nM and 0.9 nM respectively). LIMK-IN-1 can be used for research of ocular hypertension and associated glaucoma[1].
Web ID
– HY-14227
Shipping
– Room temperature
Molecular Formula
– C20H21BrN8
References
– [1]Harrison BA, et al. Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52(21):6515-8.|[2]Harrison BA, et.al. Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52(21):6515-8.
CAS Number
– 1116571-01-7
Molecular Weight
– 453.34
SMILES
– CC1=CNC2=NC=NC(N3C[C@H](C)N(/C(NC4=CC=CC(Br)=C4)=NC#N)CC3)=C21
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– LIM Kinase (LIMK);ROCK
Isoform
– LIMK1;LIMK2;ROCK1;ROCK2
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
