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LH846
$70 – $300
Products Details
Product Description
– LH846 is a selective inhibitor of CKIδ, with an IC50 of 290 nM, and less potently inhibits CKIα and CKIε, with IC50s of 2.5 μM and 1.3 μM, respectively.
Web ID
– HY-15704
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H13ClN2OS
References
– [1]Lee JW, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11.
CAS Number
– 639052-78-1
Molecular Weight
– 316.81
Compound Purity
– 98.04
SMILES
– O=C(NC1=NC2=CC(Cl)=C(C)C=C2S1)CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 45 mg/mL
Target
– Casein Kinase
Isoform
– CK1
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
