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LG100754
$400 – $1,570
Products Details
Product Description
– LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR[1].
Web ID
– HY-108523
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C26H36O3
References
– [1]Cesario RM, et al. The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo. Mol Endocrinol. 2001 Aug;15(8):1360-9.
CAS Number
– 180713-37-5
Molecular Weight
– 396.56
Compound Purity
– 99.0
SMILES
– C/C(C1=C(OCCC)C=C2C(C)(C)CCC(C)(C)C2=C1)=C/C=C/C(C)=C/C(O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– RAR/RXR
Isoform
– PPARα;PPARγ
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
