LG100754

$400$1,570

Products Details

Product Description

– LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR[1].

Web ID

– HY-108523

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C26H36O3

References

– [1]Cesario RM, et al. The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo. Mol Endocrinol. 2001 Aug;15(8):1360-9.

CAS Number

– 180713-37-5

Molecular Weight

– 396.56

Compound Purity

– 99.0

SMILES

– C/C(C1=C(OCCC)C=C2C(C)(C)CCC(C)(C)C2=C1)=C/C=C/C(C)=C/C(O)=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– RAR/RXR

Isoform

– PPARα;PPARγ

Pathway

– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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