Products Details

Product Description

– Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the research of acute pancreatitis.

Web ID

– HY-105198

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H30N4O4S

References

– [1]Kingsnorth AN, Galloway SW, Formela LJ. Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg. 1995;82(10):1414-1420. |[2]Galloway SW, Kingsnorth AN. Lung injury in the microembolic model of acute pancreatitis and amelioration by lexipafant (BB-882), a platelet-activating factor antagonist. Pancreas. 1996;13(2):140-146.

CAS Number

– 139133-26-9

Molecular Weight

– 458.57

SMILES

– CC1=NC2=CN=CC=C2N1CC3=CC=C(C=C3)S(N(C)[C@@H](CC(C)C)C(OCC)=O)(=O)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Platelet-activating Factor Receptor (PAFR)

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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