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Lexipafant
SKU
HY-105198-Get quote
Category Reference compound
Tags GPCR/G Protein, Inflammation/Immunology, Platelet-activating Factor Receptor (PAFR)
Products Details
Product Description
– Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the research of acute pancreatitis.
Web ID
– HY-105198
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H30N4O4S
References
– [1]Kingsnorth AN, Galloway SW, Formela LJ. Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg. 1995;82(10):1414-1420. |[2]Galloway SW, Kingsnorth AN. Lung injury in the microembolic model of acute pancreatitis and amelioration by lexipafant (BB-882), a platelet-activating factor antagonist. Pancreas. 1996;13(2):140-146.
CAS Number
– 139133-26-9
Molecular Weight
– 458.57
SMILES
– CC1=NC2=CN=CC=C2N1CC3=CC=C(C=C3)S(N(C)[C@@H](CC(C)C)C(OCC)=O)(=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Platelet-activating Factor Receptor (PAFR)
Pathway
– GPCR/G Protein
Product type
– Reference compound
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