Lexatumumab

SKU HY-P99299-1 mg Category Tags ,

$300$1,250

Products Details

Product Description

– Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research[1].

Web ID

– HY-P99299

Storage Temperature

– Store at -80°C for 2 years

Shipping

– Dry Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– N/A

References

– [1]Belyanskaya LL, et al. Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin. Mol Cancer. 2007 Oct 22;6:66.|[2]Engesæter B, et al. Dacarbazine and the agonistic TRAIL receptor-2 antibody lexatumumab induce synergistic anticancer effects in melanoma. PLoS One. 2012;7(9):e45492.

CAS Number

– 845816-02-6

Molecular Weight

– 143.6 (kDa)

Compound Purity

– 96.95

SMILES

– [Lexatumumab]

Clinical Information

– Phase 1

Research Area

– Cancer

Solubility

– H2O

Target

– Apoptosis

Pathway

– Apoptosis

Product type

– Inhibitory Antibodies

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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