Products Details

Product Description

– Levoleucovorin (Levofolinic acid) is the pharmacologically active levoisomer of racemic leucovorin. Levoleucovorin can be used as a rescue agent after high-dose Methotrexate (HY-14519) therapy, and in combination with fluorouracil for the research of advanced metastatic colorectal cancer[1].

Web ID

– HY-127009

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C20H23N7O7

References

– [1]Chuang VT, et al. Levoleucovorin as replacement for leucovorin in cancer treatment. Ann Pharmacother. 2012 Oct;46(10):1349-57.

CAS Number

– 68538-85-2

Molecular Weight

– 473.44

SMILES

– O=CN1C2=C(NC(N)=NC2=O)NC[C@@H]1CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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