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Leukotriene D4-d5
$1,100
Only 1000 item(s) left in stock.
Products Details
Product Description
– Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.
Web ID
– HY-113456S
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Molecular Formula
– C25H35D5N2O6S
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1240398-17-7
Molecular Weight
– 501.69
Compound Purity
– 98.0
SMILES
– N[C@@H](CS[C@H](/C=C/C=C/C=CC/C=CCCCC([2H])(C([2H])([2H])[2H])[2H])[C@H](CCCC(O)=O)O)C(NCC(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Endogenous Metabolite;Isotope-Labeled Compounds
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
