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LED209
$31 – $220
Products Details
Product Description
– LED209 is a potent small molecule inhibitor of the bacterial receptor QseC and a potent prodrug with high selectivity for QseC.
Web ID
– HY-19748
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H17N3O2S2
References
– [1]Curtis MM, et al. QseC inhibitors as an antivirulence approach for Gram-negative pathogens. MBio. 2014 Nov 11;5(6):e02165.|[2]Harrison CF, et al. Adrenergic antagonists restrict replication of Legionella. Microbiology. 2015 Jul;161(7):1392-406.|[3]Rasko DA, et al. Targeting QseC signaling and virulence for antibiotic development. Science. 2008 Aug 22;321(5892):1078-80.
CAS Number
– 245342-14-7
Molecular Weight
– 383.49
Compound Purity
– 98.87
SMILES
– O=S(C1=CC=C(NC(NC2=CC=CC=C2)=S)C=C1)(NC3=CC=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.