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Lecimibide
$240
Only 1000 item(s) left in stock.
Products Details
Product Description
– Lecimibide (DuP 128) is a potent and specific acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor for antihyperlipidemia research[1][2].
Web ID
– HY-16281
Shipping
– Room temperature
Molecular Formula
– C34H40F2N4OS
References
– [1]L J Wilcox, et al. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J Lipid Res. 2001 May;42(5):725-34. |[2]J R Burnett, et al. Inhibition of cholesterol esterification by DuP 128 decreases hepatic apolipoprotein B secretion in vivo: effect of dietary fat and cholesterol. Biochim Biophys Acta. 1998 Jul 31;1393(1):63-79.
CAS Number
– 130804-35-2
Molecular Weight
– 590.77
SMILES
– O=C(NC1=CC=C(F)C=C1F)N(CCCCCSC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2)CCCCCCC
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Acyltransferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
