LDN-91946

$32$120

Products Details

Product Description

– LDN-91946 is a potent, selective and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM[1].

Web ID

– HY-12989

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C15H10N2O4S

References

– [1]Mermerian AH, et al. Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32.

CAS Number

– 439946-22-2

Molecular Weight

– 314.32

Compound Purity

– 98.70

SMILES

– OC(C1=CC2=C(SC(C(C3=CC=CC=C3)=O)=C2N)NC1=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Neurological Disease

Solubility

– DMSO : 83.33 mg/mL (ultrasonic)

Target

– Deubiquitinase

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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