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LDN-91946
SKU
HY-12989-10 mg
Category Reference compound
Tags Cancer; Neurological Disease, Cell Cycle/DNA Damage, Deubiquitinase
$32 – $120
Products Details
Product Description
– LDN-91946 is a potent, selective and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM[1].
Web ID
– HY-12989
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H10N2O4S
References
– [1]Mermerian AH, et al. Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32.
CAS Number
– 439946-22-2
Molecular Weight
– 314.32
Compound Purity
– 98.70
SMILES
– OC(C1=CC2=C(SC(C(C3=CC=CC=C3)=O)=C2N)NC1=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– Deubiquitinase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.