LCL521

$350$2,650

Products Details

Product Description

– LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase)[1].

Web ID

– HY-103593

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C31H52N4O7

References

– [1]Bai A, et al. Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs. Bioorg Med Chem. 2014 Dec 15;22(24):6933-44.

CAS Number

– 1226851-11-1

Molecular Weight

– 592.77

Compound Purity

– 95.0

SMILES

– O=C(CN(C)C)O[C@H](C1=CC=C([N+]([O-])=O)C=C1)[C@@H](COC(CN(C)C)=O)NC(CCCCCCCCCCCCC)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO|10 mM in H2O

Target

– Phospholipase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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