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Products Details
Product Description
– LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].
Web ID
– HY-101280A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H31ClN6O2
References
– [1]Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017;7:42728. Published 2017 Feb 16.
CAS Number
– 742064-38-6
Molecular Weight
– 531.05
SMILES
– O=C(NCC1=CC=CN=C1)C2=CC=C(OCC3=CC4=CN=C(C#N)N=C4N3CCC5CCCCC5)C=C2.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NAMPT
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
