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Laxiflorin B-4
SKU
HY-156394-Get quote
Category Reference compound
Tags Cancer, ERK, MAPK/ERK Pathway;Stem Cell/Wnt
Products Details
Product Description
– Laxiflorin B-4 is modificative compound of Laxiflorin B (HY-156393), exhibited higher affinity for ERK1/2 and stronger tumor suppression[1].
Web ID
– HY-156394
Shipping
– Room temperature
Molecular Formula
– C29H29N3O6
References
– [1]Cheng-Yao Chiang, et al. A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer. Acta Pharmacol Sin. 2023 Oct 10.
Molecular Weight
– 515.56
SMILES
– O=C1[C@@](C2[C@@]3(C[C@@H](CC2)C4=C)C4=O)([C@@H](C(C)(C=C1)C)COC(C5=CN(N=C5)C6=CC=CN=C6)=O)COC3=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– ERK
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
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