Products Details

Product Description

– Laxiflorin B-4 is modificative compound of Laxiflorin B (HY-156393), exhibited higher affinity for ERK1/2 and stronger tumor suppression[1].

Web ID

– HY-156394

Shipping

– Room temperature

Molecular Formula

– C29H29N3O6

References

– [1]Cheng-Yao Chiang, et al. A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer. Acta Pharmacol Sin. 2023 Oct 10.

Molecular Weight

– 515.56

SMILES

– O=C1[C@@](C2[C@@]3(C[C@@H](CC2)C4=C)C4=O)([C@@H](C(C)(C=C1)C)COC(C5=CN(N=C5)C6=CC=CN=C6)=O)COC3=O

Clinical Information

– No Development Reported

Research Area

– cancer

Solubility

– 10 mM in DMSO

Target

– ERK

Pathway

– MAPK/ERK Pathway;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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