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Latrepirdine (dihydrochloride)
$55 – $792
Products Details
Product Description
– Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.
Web ID
– HY-14537
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C21H27Cl2N3
References
– [1]Steele JW, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer’s mouse model. Mol Psychiatry. 2013 Aug;18(8):889-97.
CAS Number
– 97657-92-6
Molecular Weight
– 392.37
Compound Purity
– 99.71
SMILES
– CN(C1)CCC2=C1C3=CC(C)=CC=C3N2CCC4=CN=C(C)C=C4.Cl.Cl
Clinical Information
– Launched
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : 6.4 mg/mL (warming)|H2O : 100 mg/mL (ultrasonic)
Target
– 5-HT Receptor;Adrenergic Receptor;Amyloid-β;Autophagy;Histamine Receptor
Pathway
– Autophagy;GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
