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Lartesertib
SKU
HY-150617-10 mg
Category Reference compound
Tags ATM/ATR, Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR
$400 – $3,400
Products Details
Product Description
– Lartesertib (M4076) is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1)[1].
Web ID
– HY-150617
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H21FN6O3
References
– [1]Alessandra AMBRUOSI, et al. Pharmaceutical preparation. WO2022058351A1.
CAS Number
– 2495096-26-7
Molecular Weight
– 448.45
Compound Purity
– 99.89
SMILES
– O=C(N1C2=C(F)C=NC=C2OC)N(C)C3=C1C4=CC(C5=CN(C)N=C5C)=C(OC)C=C4N=C3
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– ATM/ATR
Isoform
– ATM
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.