Lapatinib Ditosylate

SKU T6235-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 240 CAD

Products Details

Product Description

– Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).

Web ID

– T6235

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H26ClFN4O4S·2C7H8O3S

References

– Rusnak DW, et al. The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo. Mol Cancer Ther. 2001 Dec;1(2):85-94

CAS Number

– 388082-77-7

Molecular Weight

– C29H26ClFN4O4S·2C7H8O3S

Compound Purity

– 0.9941

SMILES

– CC1=CC=C(C=C1)S(O)(=O)=O.CC1=CC=C(C=C1)S(O)(=O)=O.CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(NC3=CC=C(OCC4=CC(F)=CC=C4)C(Cl)=C3)N=CN=C2C=C1

Pathway

– Angiogenesis|||Autophagy|||Tyrosine Kinase/Adaptors|||Apoptosis|||JAK/STAT signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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