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Lamivudine
SKU
HY-B0250-100 mg
Category Reference compound
Tags Anti-infection, HBV;HIV;Reverse Transcriptase, Infection; Cancer
$103 – $262
Products Details
Product Description
– Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].
Web ID
– HY-B0250
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C8H11N3O3S
References
– [1]Colledge D, et al. Synergistic inhibition of hepadnaviral replication by lamivudine in combination with penciclovir in vitro. Hepatology. 1997 Jul;26(1):216-25. |[2]Olaniyan LW, et al. Lamivudine-Induced Liver Injury. Open Access Maced J Med Sci. 2015 Dec 15;3(4):545-50. |[3]Mdanda S, et al. Zidovudine and Lamivudine as Potential Agents to Combat HIV-Associated Neurocognitive Disorder. Assay Drug Dev Technol. 2019 Oct;17(7):322-329.Â
CAS Number
– 134678-17-4
Molecular Weight
– 229.26
Compound Purity
– 99.97
SMILES
– OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
Target
– HBV;HIV;Reverse Transcriptase
Pathway
– Anti-infection
Product type
– Reference compound
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