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Products Details
Product Description
– Lacutoclax is a Bcl-2 inhibitor with antineoplastic activity[1].
Web ID
– HY-156620
Shipping
– Room temperature
Molecular Formula
– C48H55ClN8O7S
References
– [1]Chen Yi, et al. Preparation of condensed heterocyclic derivatives as Bcl-2 inhibitors for the treatment of neoplastic diseases. World Intellectual Property Organization, WO2019040573 A1. 2019-02-28.
CAS Number
– 2291166-56-6
Molecular Weight
– 923.52
SMILES
– O=S(NC(C1=C(C=C(N2CCN(CC2)CC3=C(C4=CC=C(C=C4)Cl)CC(C)(CC3)C)C=C1)N5C6=C(O[C@@H](C5)C)NC7=NC=CC7=C6)=O)(C8=CC([N+]([O-])=O)=C(C=C8)NCC9CCOCC9)=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
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