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Products Details
Product Description
– L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity[1].
Web ID
– HY-115737
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H50N2O3
References
– [1]Subhash Basu, et al. Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP. Glycoconj J. 2004;20(3):157-68.
CAS Number
– 207278-87-3
Molecular Weight
– 474.72
SMILES
– CCCCCCCCCCCCCCCC(N[C@@H](CN1CCOCC1)[C@@H](O)C2=CC=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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