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L-threo Lysosphingomyelin (d18:1)
$1,100
Only 1000 item(s) left in stock.
Products Details
Product Description
– L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively[1].
Web ID
– HY-113934
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H49N2O5P
References
– [1]Im DS, et al. Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. Biochemistry. 2001;40(46):14053-14060.
CAS Number
– 105615-55-2
Molecular Weight
– 464.62
Compound Purity
– 98.0
SMILES
– O=P(OCC[N+](C)(C)C)(OC[C@H](N)[C@@H](O)/C=C/CCCCCCCCCCCCC)[O-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– LPL Receptor
Isoform
– S1PR1;S1PR2;S1PR3
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
