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L-Phenylalanine-15N,d8
$50
Only 1000 item(s) left in stock.
Products Details
Product Description
– L-Phenylalanine-15N,d8 is the deuterium and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca2+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Web ID
– HY-N0215S14
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9H3D8 15NO2
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
Molecular Weight
– 174.23
Compound Purity
– 99.90
SMILES
– [15NH2][C@](C([2H])([2H])C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])([2H])C(O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– H2O : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Calcium Channel;Endogenous Metabolite;iGluR;Isotope-Labeled Compounds
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
