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Products Details
Product Description
– L-I-OddU, a L-5′-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC50 value of 0.03μM. L-I-OddU has low cytotoxicity with a CC50 value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis[1][2].
Web ID
– HY-148170
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C8H9IN2O5
References
– [1]Kira T, et, al. Anti-Epstein-Barr virus (EBV) activity of beta-L-5-iododioxolane uracil is dependent on EBV thymidine kinase. Antimicrob Agents Chemother. 2000 Dec;44(12):3278-84.|[2]Focher F, et, al. Antivirals at the mirror: the lack of stereospecificity of some viral and human enzymes offers novel opportunities in antiviral drug development. Curr Drug Targets Infect Disord. 2003 Mar;3(1):41-53.
CAS Number
– 207920-87-4
Molecular Weight
– 340.07
SMILES
– OC[C@@H]1O[C@H](N(C=C(C(N2)=O)I)C2=O)CO1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;EBV;Nucleoside Antimetabolite/Analog
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
