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L-Arginine-15N2 (hydrochloride)
$193 – $960
Products Details
Product Description
– L-Arginine-15N2 (hydrochloride) is the 15N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Web ID
– HY-N0455AS
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Molecular Formula
– C6H15ClN2 15N2O2
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12.|[3]Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45.|[4]Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17.
CAS Number
– 204633-92-1
Molecular Weight
– 212.65
Compound Purity
– 98.0
SMILES
– N[C@H](C(O)=O)CCCNC([15NH2])=[15NH].Cl
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– H2O : ≥ 25 mg/mL
Target
– Endogenous Metabolite;NO Synthase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
