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L-156602
$526
Only 1000 item(s) left in stock.
Products Details
Product Description
– L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH)[1][2].
Web ID
– HY-16384
Shipping
– Room temperature
Molecular Formula
– C38H64N8O13
References
– [1]Tsuji RF, et al. Effects of L-156,602, a C5a receptor antagonist, on mouse experimental models of inflammation. Biosci Biotechnol Biochem. 1992 Dec;56(12):2034-6.|[2]Tsuji RF, et al. Anti-inflammatory effects and specificity of L-156,602: comparison of effects on concanavalin A and zymosan-induced footpad edema, and contact sensitivity response. Immunopharmacology. 1995 Feb;29(1):79-87.
CAS Number
– 125228-51-5
Molecular Weight
– 840.96
SMILES
– CC[C@@H](C[C@H]1CC[C@@]([C@@](C(N[C@H]2[C@H](C(C)C)OC([C@@H](C)N(O)C([C@H]3CCCNN3C(CNC([C@H](C)N(O)C([C@@H]4CCCNN4C2=O)=O)=O)=O)=O)=O)=O)(O)C)(O)O[C@@H]1C)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Complement System
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
