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KYN-101
$180 – $1,200
Products Details
Product Description
– KYN-101 is a potent, selective and orally active AHR inhibitor. KYN-101 decreases the CYP1A1 mRNA expression. KYN-101 shows anti-cancer activity[1].
Web ID
– HY-134217
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C22H19FN6
References
– [1]Campesato LF, et al. Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine. Nat Commun. 2020 Aug 11;11(1):4011.
CAS Number
– 2247950-73-6
Molecular Weight
– 386.42
Compound Purity
– 98.17
SMILES
– CC1=C2N=C(C3=CC(F)=CN=C3)C=C(NCCC4=CNC5=C4C=CC=C5)N2N=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Aryl Hydrocarbon Receptor
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
