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Kuraridine
$425
Only 1000 item(s) left in stock.
Products Details
Product Description
– Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC50=0.64 μM)[1].
Web ID
– HY-121381
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C26H30O6
References
– [1]Hye Joo Shin, et al. A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2313-6.|[2]Xinzhou Yang, et al. HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root). Mol Divers. 2011 May;15(2):361-72.
CAS Number
– 34981-25-4
Molecular Weight
– 438.51
Compound Purity
– 98.0
SMILES
– O=C(C1=C(OC)C=C(O)C(C[C@H](C(C)=C)C/C=C(C)C)=C1O)/C=C/C2=CC=C(O)C=C2O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Phosphodiesterase (PDE)
Isoform
– PDE5
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
