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Products Details
Product Description
– Kuguaglycoside C is a triterpene glycoside that can be isolated from the leaves of Momordica charantia. Kuguaglycoside C induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF)[1].
Web ID
– HY-113915
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H56O8
References
– [1]Tabata K, et al. Kuguaglycoside C, a constituent of Momordica charantia, induces caspase-independent cell death of neuroblastoma cells. Cancer Sci. 2012 Dec;103(12):2153-8.
CAS Number
– 1041631-93-9
Molecular Weight
– 616.83
SMILES
– C=C(C)/C=C/C[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CC2)(C)[C@]([C@]2(C=O)[C@@](CC[C@H](O)C3(C)C)([H])C3=C4)([H])[C@H]4O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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