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Products Details
Product Description
– KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
Web ID
– HY-116169
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C21H27NO5
References
– [1]Igawa Y, Schneider T, Yamazaki Y, et al. Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322. Naunyn Schmiedebergs Arch Pharmacol. 2012;385(8):759-767.|[2]Abe Y, Nakano Y, Kanazawa T, Furihata T, Endo T, Kobayashi M. Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men. Clin Pharmacol Drug Dev. 2016;5(3):201-207.
CAS Number
– 255734-04-4
Molecular Weight
– 373.44
SMILES
– O=C(COC1=CC(C)=C(C=C1C)CCN[C@H]([C@@H](C2=CC=C(C=C2)O)O)C)O
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– β adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
