Products Details

Product Description

– KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.

Web ID

– HY-116169

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C21H27NO5

References

– [1]Igawa Y, Schneider T, Yamazaki Y, et al. Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322. Naunyn Schmiedebergs Arch Pharmacol. 2012;385(8):759-767.|[2]Abe Y, Nakano Y, Kanazawa T, Furihata T, Endo T, Kobayashi M. Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men. Clin Pharmacol Drug Dev. 2016;5(3):201-207.

CAS Number

– 255734-04-4

Molecular Weight

– 373.44

SMILES

– O=C(COC1=CC(C)=C(C=C1C)CCN[C@H]([C@@H](C2=CC=C(C=C2)O)O)C)O

Clinical Information

– No Development Reported

Research Area

– Endocrinology; Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Adrenergic Receptor

Isoform

– β adrenergic receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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