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Products Details
Product Description
– KTX-497 is an IRAK4 degrader with a DC50 value of 3 nM. KTX-497 can be used for the research of oncology[1].
Web ID
– HY-148276
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C45H49F3N8O6
References
– [1]Discovery and characterization of IRAKIMiDs: degraders targeting both IRAK4 and IMiD substrates for oncology indications.
CAS Number
– 2432993-46-7
Molecular Weight
– 854.92
SMILES
– O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(NC4CC5(CCN(CC5)C[C@@H]6CC[C@@H](N7C=C8C(C=C(C(NC(C9=CC=CC(C(F)(F)F)=N9)=O)=C8)C(C)(O)C)=N7)CC6)C4)=C3C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IRAK
Isoform
– IRAK4
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
