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KT-531
$461
Only 1000 item(s) left in stock.
Products Details
Product Description
– KT-531 is a potent and selective inhibitor of HDAC6 with an IC50 of 8.5 nM. KT-531 exhibits strong inhibition against SUP-T11 cells with an IC50 of 0.42 μM. KT-531 can be used in study hematological cancers[1].
Web ID
– HY-128436
Shipping
– Room temperature
Molecular Formula
– C17H14F4N2O4S
References
– [1]Toutah K, et al. Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia. J Med Chem. 2021 Jun 24;64(12):8486-8509.
CAS Number
– 2490284-18-7
Molecular Weight
– 418.36
SMILES
– O=C(NO)C1=CC=C(CN(C2CC2)S(=O)(C3=CC(F)=C(F)C(F)=C3F)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
